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JAGGED-1 PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
Jagged-1 Protein
Descriptor
Spanish
:
Proteína Jagged-1
Descriptor
Portuguese
:
Proteína Jagged-1
Synonyms
English
:
Alagille Syndrome Protein
CD339 Antigen
Jagged-1
Jagged1 Protein
Serrate-1 Protein
Serrate1 Protein
Antigen, CD339
Jagged 1
Jagged 1 Protein
Serrate 1 Protein
Tree Number:
D12.644.276.930.500
D12.776.157.125.797.500
D12.776.543.800.500
D23.050.301.264.035.438
D23.101.100.110.438
D23.529.930.500
Definition
English
:
A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate
CELL DIFFERENTIATION
in
HEMATOPOIESIS
and PHYSIOLOGIC ANGIOGENESIS.
Mutations
in the Jagged-1 gene are associated with
ALAGILLE SYNDROME
1.
History Note
English
:
2017 (1991)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56530
Unique Identifier:
D000072100
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS